Senior Principal AWS Cloud Architect

Company: Initial Therapeutics, Inc.
Location: Washington
Posted on: June 1, 2025

Job Description:

Join Amgens Mission of Serving PatientsAt Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do.Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.Senior Principal AWS Cloud ArchitectWhat you will doLets do this. Lets change the world. In this vital role you will serve as a technical visionary and hands-on technical leader for the design, development, and evolution of our enterprise-grade Amgen Cloud Platform. This role is pivotal in driving our cloud-first strategy by delivering secure, scalable, and high-performance cloud platform to power global research, manufacturing, and digital products.As a Senior Principal Architect, you will influence platform design decisions, coach engineering teams, and define best practices while remaining deeply hands-on with AWS services and infrastructure as code.Key Responsibilities:

• Lead the architecture and technical direction of the Amgen Cloud Platform on AWS.
• Define and enforce cloud-native architecture standards, patterns, and reusable components.
• Build scalable, secure, and compliant landing zones using AWS Control Tower, Organizations, SCPs, IAM, etc.
• Collaborate across security, data, DevOps, and application teams to design integrated solutions.
• Drive adoption of Infrastructure as Code (IaC) using tools like Terraform or AWS CDK.
• Evaluate and introduce emerging AWS services and architectural innovations into the platform.
• Provide architecture governance, design reviews, and mentorship to engineers and junior architects.
• Troubleshoot and resolve complex issues in cloud-native deployments and enterprise integrations.
• Contribute to Amgens cloud roadmap, reference architectures, and architectural principles.What we expect of youWe are all different, yet we all use our unique contributions to serve patients. The AWS Architect professional we seek is a problem solver with these qualifications.Basic Qualifications:Doctorate degree and 3 years of Computer Science or Information Technology experienceOrMasters degree and 5 years of Computer Science or Information Technology experienceOrBachelors degree and 7 years of Computer Science or Information Technology experienceOrAssociates degree and 12 years of Computer Science or Information Technology experienceOrHigh school diploma / GED and 14 years of Computer Science or Information Technology experience-Preferred Qualifications:Must-Have Skills:
  • 14+ years of experience in IT with 8+ years of AWS architecture and engineering.
  • Demonstrated expertise in designing enterprise-scale platforms on AWS (multi-account, multi-region, secure).
  • Solid command of core AWS services: EC2, S3, Lambda, ECS/EKS, VPC, IAM, KMS, CloudFormation/Terraform, Control Tower, Config, GuardDuty, etc.
  • Deep knowledge of networking, security, and identity in AWS (VPC peering, PrivateLink, Transit Gateway, SCPs, IAM Roles & Policies).
  • Strong hands-on expertise in Infrastructure as Code (Terraform or AWS CDK preferred).
  • Experience with CI/CD pipelines, preferably using GitLab, or similar.
  • Demonstrated ability to lead architectural design sessions, influence technical direction, and mentor teams.
  • Solid understanding of compliance and security standards (e.g., HIPAA, GxP, NIST, CIS Benchmarks).
  • Experience leading Well-Architected Reviews and aligning designs with AWS standard methodologies.
  • Good communication and collaborator engagement skills.Good-to-Have Skills:
    • AWS Certified: Solutions Architect Professional, or other specialty certifications.
    • Experience with Kubernetes (EKS), serverless patterns, and event-driven architectures.
    • Familiarity with multi-cloud architecture, though AWS is primary.
    • Experience working in regulated industries, particularly biotech or pharma.
    • Familiarity with FinOps, tagging strategies, and cost optimization in AWS.
    • Exposure to data platforms on AWS (e.g., Lake Formation, Glue, Redshift).
    • Knowledge of ServiceNow, HashiCorp Vault, or Splunk in cloud ecosystems.What you can expect of usAs we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way.The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:
      • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
      • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
      • Stock-based long-term incentives
      • Award-winning time-off plans
      • Flexible work models, including remote and hybrid work arrangements, where possibleApply now and make a lasting impact with the Amgen team.careers.amgen.comIn any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.Application deadlineAmgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.
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Keywords: Initial Therapeutics, Inc., Wheaton-Glenmont , Senior Principal AWS Cloud Architect, Professions , Washington, Maryland